CHEM5625 — Chemistry and Design of Protein Pharmaceuticals: Reviews & Ratings

CHEM5625 (Chemistry and Design of Protein Pharmaceuticals) course reviews and ratings at Northeastern (NEU). Compare professors with RateMyProfessor reviews.

Covers the chemical transformations and protein engineering approaches to protein pharmaceuticals. Describes protein posttranslational modifications, such as oxidation, glycosylation, formation of isoaspartic acid, and disulfide. Then discusses bioconjugate chemistry, including those involved in antibody-drug conjugate and PEGylation. Finally, explores various protein engineering approaches, such as quality by design (QbD), to optimize the stability, immunogenicity, activity, and production of protein pharmaceuticals. Discusses the underlying chemical principles and enzymatic mechanisms as well.

Last taught

Fall 2025

Credits

3 Hours

Prerequisites

(CHEM 2317 with a minimum grade of C- or CHEM 2313 with a minimum grade of C- or graduate program admission); (CHEM 5620 (may be taken concurrently) with a minimum grade of C- or CHEM 5620 (may be taken concurrently) with a minimum grade of C- or CHEM 5621 (may be taken concurrently) with a minimum grade of C- or CHEM 5621 (may be taken concurrently) with a minimum grade of C- )

Data updated October 2026.

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